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Endometrial Cancer Treatment

Duped by your Endometrial Cancer?

Endometrial cancer is the most frequently occurring malignancy of the female genital tract and cases of such diseases are on the surge. Endometrial cancer treatment in India offers a ray of hope among women who are ailing. Such type of cancer originates from the endometrium (which lines the womb), resulting in uncontrolled growth of cells that have the potential to infect other parts of the body too.

The most prominent sign of endometrial cancer is unusual vaginal bleeding, which has no link to menstrual bleeding. Such type of cancer is common among women who are through their menopause stage.  Of all the endometrial cancer cases, 40 percent are those of obese women.

Symptoms of Endometrial Cancer

Some of the common signs and symptoms of endometrial cancer are as follows:

•    Postmenopause vaginal bleeding

•    Unusual Bleeding during periods

•    Abnormal Menstrual Cycles

  • An irregular, alkaline and watery discharge from the vagina

•    Spotting

•    Pelvic pain

•    Difficulty while urinating

•    Painful Sexual Intercourse

Risk Factors for Endometrial Cancer

Sone of the known risk factors for endometrial cancer are as follows:

•    Obesity

•    Diabetes Mellitus

•    Early onset of mensuration (before the age of 12)

•    Breast Cancer

•    Exposure to tamoxifen

•    Delay in Menopause

•    Women who could never get pregnant

•    Escalated Oestrogen Levels

•    Polycystic Ovary Syndrome (PCOS)

•    Ageing

•    Smoking

•    Inherited Genetic Conditions such as Cowden Syndrome

•    Inherited Colon Cancer Syndrome

•    Elevated Blood Pressure

•    Weaker Immune System

It has been found out that higher body mass index is associated with causing inflammation which hinders the mechanism of cytokines.

Immigration studies, which closely analysed the alteration in cancer likelihood among populaces moving from one country to another with different rates of cancer, revealed a minor association between an environmental component and endometrial cancer. However, these toxic environmental components not have been wholly classified to be the contributors; the study warrants further research.

Diagnosis of Endometrial Cancer

Various tests and procedures that one needs to undergo for diagnosis of endometrial cancer are as follows:

Pelvic examination– This procedure involves conducting a pelvic exam by inspecting the outer portion of one’s vulva by inserting a device known a speculum into your vagina.

A transvaginal ultrasound, which involves inserting a wandlike device into the vagina. The device, known as the transducer, via sound energy dispenses video of the uterus. This procedure is performed to monitor the thickness and texture of the endometrium and help rule out the abnormalities if any persist. Hysteroscopy- The process involves inserting a hysteroscope, this procedure is termed as hysteroscopy, which holds potential in examining uterine and the endometrium lining.

Endometrial Biopsy – This procedure involves extracting a sample of tissue which is then sent to the laboratory for examination.

Surgical removal of tissue for examination– Surgical tests are performed when the biopsy results are vague. This procedure involves scraping the tissue from the uterine lining via dilation and curettage (D&C) so that cancer traces can be analysed.

Endometrial Cancer Treatment

The treatment one undergoes for endometrial cancer depends on the type, stage, grade, sight and severity of cancer. There are three ways of going about the treatment, but then some options may be closed for some patients, depending upon their health. One can either get the cancer removed surgically or may undergo various therapies. At times, radiation therapy is given alongside surgery. 

•    Surgery

Surgery involves removal of the uterus via performing a hysterectomy.  At times it also mandates removal of fallopian tubes and ovaries, which is done via performing salpingo-oophorectomy.

Lymph nodes may be removed for determining the stage of cancer.

•    Therapy

1.    Radiation Therapy

The procedure involves exposing the patient to high-packed energy beams such as X-rays and protons so that pathogens can be demolished. The various ways in which radiation therapy can be delivered are as follows:

External Radiation– In this procedure, the machine is placed outside your body.

Internal Radiation– Also known as brachytherapy, the procedure involves placing a radiation-filled device (small seeds, wires or a cylinder), inside the vagina.

2.    Hormone therapy

Hormone therapy involves boosting progesterone expression in the system via administering drugs. The other option involves mitigating the estrogen levels in the body. Both the techniqueshave shown potential in impeding the growth of endometrial cancer cells.

3.    Chemotherapy

The procedure involves administering drugs into the bloodstream either orally or intravenously. However, chemotherapy is recommended to only patients whose cancer is widespread or has relapsed. These drugs have proved to be of potential in shrinking the tumour.

Best Oncologists, Gynaecologist and Hospitals for Endometrial Cancer in India

•    Fortis Memorial Research Institute, Gurugram- Dr Vinod Raina

•    Fortis Flt. Lt. RajanDhall Hospital, Vasant Kunj – Dr Urvashi Jha

•    Fortis Memorial Research Institute, Gurugram – Dr Rama Joshi

•    BLK Super Speciality Hospital, New Delhi- Dr Amit Agarwal

•    Fortis Memorial Research Institute, Gurugram – Dr Rahul Bhargava

•    Max Smart Super Speciality Hospital, Saket – Dr Rahul Naithani

•    BLK Super Speciality Hospital, New Delhi- Dr Amit Agarwal

•    BLK Super Speciality Hospital, New Delhi- Dr Dharma Choudhary

How much does the Endometrial Cancer Treatment Cost in India?

Endometrial cancer treatment is low cost in India when compared to other countries. The cost of undergoing surgery for removal of the endometrial cancer is USD 8000. Radiation therapy costs near about USD 5000, and the cost of chemotherapy per cycle is USD 500.

The cost of availing ovarian cancer in India also depends on various other factors.

•    Your choice of hospital

•    Preference of the oncologist

•    The grade, type and how widespread the disease is

•    Post-surgery expenses

How can Endometrial Cancer be warded off?

A novel study conducted has potentially highlighted the role of regular exercising in averting endometrial cancer relapse. Individuals who underwent treatment for breast and colon cancer must indulge in daily aerobic physical activity so that the odds of endometrial cancer can be mitigated. The study also sheds light on the potency of consuming one cup of decaffeinated or caffeinated coffee, which cuts the overall risk by seven percent. Additionally, incorporating a whole grain diet rather than refined grains and a plant-based diet comprising leafy veggies, fruits, beans along with weight management has a strong connection with lowering the risk of cancer.

One-year intake of birth control pills recommended by gynaecologist significantly lowers the risk of endometrial cancer. One-year intake has a long-lasting impact in minimising the risk, but it is essential to discuss with your gynaecologist because these oral contraceptive pills have some side effects too.

Women who opt for hormone replacement therapy for tackling menopause symptoms should be aware of the pros and cons of the treatment and then take a call because hormone therapy may put a woman at risk of breast cancer. Refrain from being exposed this therapy if you haven’t undergone a hysterectomy.

FAQ’s

1.    What are the survival rates of Endometrial Cancer?

The survival rate for endometrial adenocarcinoma post proper treatment is 80 percent, spanning close to five years. Over 70 percent of all the cases are of FIGO stage I cancer, and it has an excellent prognosis. 13 percent of the cases which account for Stage III and Stage IV cancers don’t have that promising prognosis. However, the median duration of survival for stage III-IV endometrial cancer ranges from nine to ten months.

Prognosis among senior adults is not good. Some studies, in which American women were recruited has shed light on the association of white women having higher survival rates when compared to black women.

Cancer with high progesterone levels has a better prognosis when compared to low progesterone levels. Ailments pertaining to heart and obesity after successful treatment has a strong link to relapse or death due to cancer. However, lifestyle post-surgery has a major role to play; incorporating a healthy balanced diet and physical activity has undoubtedly good prognosis.

2.    What is palliative care and how beneficial is it for endometrial cancer?

Palliative care is given alongside treatments such as chemotherapy, radiation, surgery etc. so that the patient feels better. Delivered via a specialised class of doctors, supportive staff and other professionals; palliative care has been linked to enhancing the quality of many patients. The objective of such a technique is to relieve the patients from pain and helps them cope up with the taxing process of chemotherapy.